Daunorubicin pharmacokinetics and the correlation with P-glycoprotein and response in patients with acute leukaemia.

The aim of this study was to examine the relationship between the pharmacokinetics of daunorubicin (DNR), overexpression of P-glycoprotein (Pgp) and treatment response in acute leukaemia. Twenty-seven patients with acute leukaemia received DNR as part of induction therapy. The plasma and cellular le...

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Bibliographic Details
Main Authors: Galettis, P., Boutagy, J., Ma, D. D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033508/
https://ncbi.nlm.nih.gov/pubmed/7914424
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