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Pharmacokinetics of cytosine arabinoside in patients with acute myeloid leukaemia.

1 The pharmacokinetics of cytosine arabinoside were studied after a single i.v. bolus of 2 mg/kg ara-C in patients with newly diagnosed untreated AML, using a bioassay and GC-MS method to measure the plasma concentrations. 2 Most patients showed a bi- or tri-phasic decline in plasma concentrations w...

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Detalhes bibliográficos
Main Authors: Harris, A L, Potter, C, Bunch, C, Boutagy, J, Harvey, D J, Grahame-Smith, D G
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429786/
https://ncbi.nlm.nih.gov/pubmed/291436
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