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The p53 status of cultured human premalignant oral keratinocytes.

Around 60% of oral squamous cell carcinomas (SCCs) have been shown to harbour p53 mutations, and other studies have demonstrated mutant p53 genes in normal and dysplastic squamous epithelium adjacent to these SCCs. In line with these earlier studies we show here that DOK, a keratinocyte cell line de...

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Autori principali: Burns, J. E., Clark, L. J., Yeudall, W. A., Mitchell, R., Mackenzie, K., Chang, S. E., Parkinson, E. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033430/
https://ncbi.nlm.nih.gov/pubmed/7917902
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