Comparison of p53 gene mutation and protein overexpression in colorectal carcinomas.

Immunocytochemistry (ICC) has been used routinely to stain for p53 overexpression in a range of human tumours. The underlying assumption has been that positive staining indicates a mutation in the p53 coding sequence. Recently, however, discordancy has been observed and the accuracy of ICC as a mark...

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Bibliografiska uppgifter
Huvudupphovsmän: Dix, B., Robbins, P., Carrello, S., House, A., Iacopetta, B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033416/
https://ncbi.nlm.nih.gov/pubmed/7917901
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