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Immunohistochemical Determination of p53 Protein Overexpression for Predicting p53 Gene Mutations in Hepatocellular Carcinoma: A Meta-Analysis

BACKGROUND: Whether increased expression of the tumor suppressor protein p53 indicates a p53 gene mutation in hepatocellular carcinoma (HCC) remains unclear. We conducted a meta-analysis to determine whether p53 protein overexpression detected by immunohistochemistry (IHC) offers a diagnostic predic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Jiangbo, Li, Wei, Deng, Miao, Liu, Dechun, Ma, Qingyong, Feng, Xiaoshan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948819/
https://ncbi.nlm.nih.gov/pubmed/27428001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159636
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