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Assessment of the proliferative activity and radiosensitivity of human tumours using the cytokinesis-block micronucleus assay.

We established an in vitro cytokinesis-block micronucleus assay of human tumours for estimation of the proportion of cells undergoing mitosis (the dividing fraction, DF), the time for the number of nuclei to double and the radiosensitivity in terms of the micronucleus frequency, based on a concept d...

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Autori principali: Shibamoto, Y., Shibata, T., Miyatake, S., Oda, Y., Manabe, T., Ohshio, G., Yagi, K., Streffer, C., Takahashi, M., Abe, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033295/
https://ncbi.nlm.nih.gov/pubmed/8018543
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