Tirapazamine: hypoxic cytotoxicity and interaction with radiation as assessed by the micronucleus assay.

We investigated the cytotoxicity and the interaction with low-dose radiation (1-4Gy) of tirapazamine by the in vitro cytokinesis-block micronucleus (MN) assay. Murine SCCVII and human melanoma (G-361) cells were treated with tirapazamine under aerobic or hypoxic conditions for 1 h and the MN frequen...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shibata, T., Shibamoto, Y., Sasai, K., Oya, N., Murata, R., Takagi, T., Hiraoka, M., Takahashi, M., Abe, M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149998/
https://ncbi.nlm.nih.gov/pubmed/8763848
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires