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Use of 2-aminopurine as a fluorescent tool for characterizing antibiotic recognition of the bacterial rRNA A-site

Spectroscopic and calorimetric techniques have been employed to characterize the impact of incorporation of the fluorescent base analog 2-aminopurine into the 1492 or 1493 position of an E. coli rRNA A-site model oligonucleotide, as well as the energetics and dynamics associated with recognition of...

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Detalhes bibliográficos
Main Authors: Barbieri, Christopher M., Kaul, Malvika, Pilch, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031868/
https://ncbi.nlm.nih.gov/pubmed/18431442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2006.08.107
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