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Isoxazoles from 1,1-Disubstituted Bromoalkenes

The regioselective synthesis of 3,5-disubstituted isoxazoles was achieved through the 1,3-dipolar cycloaddition of nitrile oxides with 1,1-disubstituted bromoalkenes. The substituted bromoalkenes function as alkyne synthons which were used to construct 5,5-disubstituted bromoisoxazoline intermediate...

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Detalhes bibliográficos
Main Authors: Dadiboyena, Sureshbabu, Xu, Jianping, Hamme, Ashton T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031838/
https://ncbi.nlm.nih.gov/pubmed/18265873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.12.005
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