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Ras-independent transformation by v-Src

Signaling by a variety of receptor and nonreceptor tyrosine kinases is mediated by Ras, a membrane-associated GTPase. Expression of v-Src, a transforming nonreceptor tyrosine kinase, results in Ras activation, and inhibition of Ras function in NIH 3T3 cells suppresses transformation by v-Src, indica...

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Bibliografiske detaljer
Main Authors: Aftab, Dana T., Kwan, Joanne, Martin, G. Steven
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20316/
https://ncbi.nlm.nih.gov/pubmed/9096340
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