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3-Hydroxy-4-methoxyindolomorphinans as delta opioid selective ligands

Previous studies showed that 4-hydroxy-3-methoxyindolomorphinans had variable delta opioid affinity and selectivity. Herein we show that the 3,4-dimethoxy analogs possessed similar low affinity, whereas the 3-hydroxy-4-methoxy analogs showed excellent delta opioid affinity and selectivity comparable...

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Detalhes bibliográficos
Main Authors: Smith, Trudy A., Thatcher, Linn N., Coop, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2030991/
https://ncbi.nlm.nih.gov/pubmed/17659872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.06.087
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