Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-κB activation and alleviates myocardial ischemia/reperfusion injury

Acute myocardial infarction (AMI) remains the leading cause of death in developed countries. Although reperfusion of coronary arteries reduces mortality, it is associated with tissue injury. Endothelial P-selectin–mediated infiltration of neutrophils plays a key role in reperfusion injury. However,...

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Main Authors: Izumi, Takehiko, Saito, Yoshihiko, Kishimoto, Ichiro, Harada, Masaki, Kuwahara, Koichiro, Hamanaka, Ichiro, Takahashi, Nobuki, Kawakami, Rika, Li, Yuhao, Takemura, Genzo, Fujiwara, Hisayoshi, Garbers, David L., Mochizuki, Seibu, Nakao, Kazuwa
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC203025/
https://ncbi.nlm.nih.gov/pubmed/11457873
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