The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenon

The kidneys “escape” from the Na-retaining effects of aldosterone when circulating levels of aldosterone are inappropriately elevated in the setting of normal or expanded extracellular fluid volume, e.g., in primary aldosteronism. Using a targeted proteomics approach, we screened renal protein extra...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Wang, Xiao-Yan, Masilamani, Shyama, Nielsen, Jakob, Kwon, Tae-Hwan, Brooks, Heddwen L., Nielsen, Søren, Knepper, Mark A.
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 2001
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11457874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10366
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