Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities

Npt2 encodes a renal-specific, brush-border membrane Na(+)-phosphate (P(i)) cotransporter that is expressed in the proximal tubule where the bulk of filtered P(i) is reabsorbed. Mice deficient in the Npt2 gene were generated by targeted mutagenesis to define the role of Npt2 in the overall maintenan...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Beck, Laurent, Karaplis, Andrew C., Amizuka, Norio, Hewson, A. Stacy, Ozawa, Hidehiro, Tenenhouse, Harriet S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20268/
https://ncbi.nlm.nih.gov/pubmed/9560283
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados