Vitamin D3 suppresses Npt2c abundance and differentially modulates phosphate and calcium homeostasis in Npt2a knockout mice

Abstract Vitamin D3 is clinically used for the treatment of vitamin D3 deficiency or osteoporosis, partially because of its role in regulating phosphate (Pi) and calcium (Ca2+) homeostasis. The renal sodium-phosphate cotransporter 2a (Npt2a) plays an important role in Pi homeostasis; however, the ro...

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Prif Awduron:	Linto Thomas, Lashodya V. Dissanayake, Maryam Tahmasbi, Alexander Staruschenko, Sima Al-Masri, Jessica A. Dominguez Rieg, Timo Rieg
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Nature Portfolio 2024-07-01
Cyfres:	Scientific Reports
Pynciau:	Calcium Fibroblast growth factor 23 Parathyroid hormone Sodium-phosphate cotransporter Vitamin D3
Mynediad Ar-lein:	https://doi.org/10.1038/s41598-024-67839-4
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