Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: Preliminary studies on therapeutic efficacy and toxicity

Studies by several investigators have shown that 12–0-tetradecanoylphorbol-13-acetate (TPA) is an extraordinarily potent stimulator of differentiation of cultured human promyelocytic leukemia cells in vitro. In the present study, TPA was administered to humans by i.v. infusion without irreversible t...

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Main Authors: Han, Zheng Tao, Zhu, Xiao Xiu, Yang, Ru Yu, Sun, Jun Zhong, Tian, Guo Fang, Liu, Xin Jian, Cao, Guo Shun, Newmark, Harold L., Conney, Allan H., Chang, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC20265/
https://ncbi.nlm.nih.gov/pubmed/9560280
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