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Transcriptional suppression of cytokine-induced iNOS gene expression by IL-13 through IRF-1/ISRE signaling

IL-13 has been reported as one of the major down-regulators of iNOS expression in various tissues and cells. The molecular mechanism of iNOS suppression by IL-13 remains unclear, especially at the transcriptional stage. In this study, we found that IL-13 inhibited the expression of iNOS mRNA, protei...

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Hlavní autoři: Shao, Lifang, Guo, Zhong, Geller, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025693/
https://ncbi.nlm.nih.gov/pubmed/17723228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.07.203
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