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Ionic Current Blockades from DNA and RNA Molecules in the α-Hemolysin Nanopore

We characterize the substate structure of current blockades produced when single-stranded polynucleotide molecules were electrophoretically driven into the α-hemolysin protein pore. We frequently observe substates where the ionic current is reduced by ∼50%. Most of these substates can be associated...

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Detalhes bibliográficos
Main Authors: Butler, Tom Z., Gundlach, Jens H., Troll, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025643/
https://ncbi.nlm.nih.gov/pubmed/17675346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.107003
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