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Predicting active site residue annotations in the Pfam database

BACKGROUND: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for catalysis determined. To increase the active site annotations in the Pfam database, we have developed a strict set of rules,...

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Main Authors: Mistry, Jaina, Bateman, Alex, Finn, Robert D
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025603/
https://ncbi.nlm.nih.gov/pubmed/17688688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-298
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