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Radiosensitizing and cytocidal effects on hypoxic cells of RO-07-0582, and repair of x-ray injury, in an experimental mouse tumour.

The delay in regrowth to 10 mm diameter of a transplanted carcinoma in mice was used to estimate the effect of the hypoxic-cell radiosensitizer Ro-07-0582. When 1 mg/g body wt. was given before a single dose of X-rays, a dose-enhancement ratio of 2-0 was found. When the drug was given immediately af...

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Autori principali: Hill, S. A., Fowler, J. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1977
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025355/
https://ncbi.nlm.nih.gov/pubmed/869984
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