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Polymicrobial Sepsis Enhances Clearance of Apoptotic Immune Cells by Splenic Macrophages

BACKGROUND: Macrophage phagocytosis of apoptotic cells induces an anti-inflammatory macrophage phenotype. Immune cell apoptosis is widespread in sepsis; however, it is unknown whether sepsis alters the capacity of macrophages to clear this expanded population. We hypothesize that sepsis will enhance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Swan, Ryan, Chung, Chun-Shiang, Albina, Jorge, Cioffi, William, Perl, Mario, Ayala, Alfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2023968/
https://ncbi.nlm.nih.gov/pubmed/17689693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2007.04.005
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