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Polymicrobial Sepsis Enhances Clearance of Apoptotic Immune Cells by Splenic Macrophages

BACKGROUND: Macrophage phagocytosis of apoptotic cells induces an anti-inflammatory macrophage phenotype. Immune cell apoptosis is widespread in sepsis; however, it is unknown whether sepsis alters the capacity of macrophages to clear this expanded population. We hypothesize that sepsis will enhance...

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Detalhes bibliográficos
Main Authors: Swan, Ryan, Chung, Chun-Shiang, Albina, Jorge, Cioffi, William, Perl, Mario, Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2023968/
https://ncbi.nlm.nih.gov/pubmed/17689693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2007.04.005
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