JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation

Lipopolysaccharide (LPS) is recognized by Toll-like receptor (TLR) 4 and activates NF-κB and a set of MAP kinases. Here we have investigated proteins associated with the cytoplasmic domain of mouse TLR4 by yeast two-hybrid screening and identified JNK-interacting protein 3 (JIP3), a scaffold protein...

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Main Authors: Matsuguchi, Tetsuya, Masuda, Akio, Sugimoto, Kenji, Nagai, Yoshiyuki, Yoshikai, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2003
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC202380/
https://ncbi.nlm.nih.gov/pubmed/12941697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg438
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