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The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation
The 20S proteasome is a large multisubunit assembly that performs most of the intracellular non-lysosomal proteolysis of eukaryotes. Substrates access the proteasome active sites, which are sequestered in the interior of the barrel-shaped structure, through pores that are opened by binding of activa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC202378/ https://ncbi.nlm.nih.gov/pubmed/12941688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg436 |
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