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Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb

The c-Myb transcription factor is expressed in immature haemopoietic cells and at key stages during differentiation. Loss of the c-myb gene results in embryonic lethality because mature blood cells fail to develop, although commitment to definitive haemopoiesis occurs. We have generated a knockdown...

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Detalhes bibliográficos
Main Authors: Emambokus, Nikla, Vegiopoulos, Alexandros, Harman, Ben, Jenkinson, Eric, Anderson, Graham, Frampton, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC202376/
https://ncbi.nlm.nih.gov/pubmed/12941699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg434
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