FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation

Phosphorylation of the Neurospora circadian clock protein FREQUENCY (FRQ) regulates its degradation and the proper function of the clock. The mechanism by which FRQ undergoes degradation has not been established. Here we show that FRQ is likely ubiquitylated in vivo, and its proper degradation requi...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	He, Qun, Cheng, Ping, Yang, Yuhong, He, Qiyang, Yu, Hongtao, Liu, Yi
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2003
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC202367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12941694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg425
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