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FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation

Phosphorylation of the Neurospora circadian clock protein FREQUENCY (FRQ) regulates its degradation and the proper function of the clock. The mechanism by which FRQ undergoes degradation has not been established. Here we show that FRQ is likely ubiquitylated in vivo, and its proper degradation requi...

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Hlavní autoři: He, Qun, Cheng, Ping, Yang, Yuhong, He, Qiyang, Yu, Hongtao, Liu, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC202367/
https://ncbi.nlm.nih.gov/pubmed/12941694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg425
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