Prolonged Toxicokinetics and Toxicodynamics of Paraquat in Mouse Brain

BACKGROUND: Paraquat (PQ) has been implicated as a risk factor for the Parkinson disease phenotype (PDP) in humans and mice using epidemiologic or experimental approaches. The toxicokinetics (TK) and toxicodynamics (TD) of PQ in the brain are not well understood. OBJECTIVES: The TK and TD of PQ in b...

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Autors principals: Prasad, Kavita, Winnik, Bozena, Thiruchelvam, Mona J., Buckley, Brian, Mirochnitchenko, Oleg, Richfield, Eric K.
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2022643/
https://ncbi.nlm.nih.gov/pubmed/17938734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9932
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