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Toward a resolution of the introns early/late debate: Only phase zero introns are correlated with the structure of ancient proteins

We present evidence that a well defined subset of intron positions shows a non-random distribution in ancient genes. We analyze a database of ancient conserved regions drawn from GenBank 101 to retest two predictions of the theory that the first genes were constructed by exon shuffling. These predic...

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Autors principals: de Souza, Sandro J., Long, Manyuan, Klein, Robert J., Roy, Scott, Lin, Shin, Gilbert, Walter
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20219/
https://ncbi.nlm.nih.gov/pubmed/9560234
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