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The Mode of Replication Is a Major Factor in Segregational Plasmid Instability in Lactococcus lactis

The effects of the rolling-circle and theta modes of replication on the maintenance of recombinant plasmids in Lactococcus lactis were studied. Heterologous Escherichia coli or bacteriophage λ DNA fragments of various sizes were inserted into vectors based on either the rolling-circle-type plasmid p...

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Detalhes bibliográficos
Main Authors: Kiewiet, Rense, Kok, Jan, Seegers, Jos F. M. L., Venema, Gerard, Bron, Sierd
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC202113/
https://ncbi.nlm.nih.gov/pubmed/16348863
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