γH2AX Foci Form Preferentially in Euchromatin after Ionising-Radiation

BACKGROUND: The histone variant histone H2A.X comprises up to 25% of the H2A complement in mammalian cells. It is rapidly phosphorylated following exposure of cells to double-strand break (DSB) inducing agents such as ionising radiation. Within minutes of DSB generation, H2AX molecules are phosphory...

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Detalhes bibliográficos
Main Authors: Cowell, Ian G., Sunter, Nicola J., Singh, Prim B., Austin, Caroline A., Durkacz, Barbara W., Tilby, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2020439/
https://ncbi.nlm.nih.gov/pubmed/17957241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001057
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