K13 Blocks KSHV Lytic Replication and Deregulates vIL6 and hIL6 Expression: A Model of Lytic Replication Induced Clonal Selection in Viral Oncogenesis

BACKGROUND: Accumulating evidence suggests that dysregulated expression of lytic genes plays an important role in KSHV (Kaposi's sarcoma associated herpesvirus) tumorigenesis. However, the molecular events leading to the dysregulation of KSHV lytic gene expression program are incompletely under...

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Detalhes bibliográficos
Main Authors: Zhao, Jinshun, Punj, Vasu, Matta, Hittu, Mazzacurati, Lucia, Schamus, Sandra, Yang, Yanqiang, Yang, Tianbing, Hong, Yan, Chaudhary, Preethello M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2020437/
https://ncbi.nlm.nih.gov/pubmed/17957251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001067
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