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Perturbation of nucleosome core structure by the SWI/SNF complex persists after its detachment, enhancing subsequent transcription factor binding

To investigate the mechanism of SWI/SNF action, we have analyzed the pathway by which SWI/SNF stimulates formation of transcription factor-bound nucleosome core complexes. We report here that the SWI/SNF complex binds directly to nucleosome cores and uses the energy of ATP hydrolysis to disrupt hist...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Côté, Jacques, Peterson, Craig L., Workman, Jerry L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560208/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.4947
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