Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins

The ability of iron to catalyze formation of reactive oxygen species significantly contributes to its toxicity in cells and animals. Iron uptake and distribution is regulated tightly in mammalian cells, in part by iron regulatory protein 2 (IRP2), a protein that is degraded efficiently by the protea...

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Αποθηκεύτηκε σε:

Λεπτομέρειες βιβλιογραφικής εγγραφής
Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Iwai, Kazuhiro, Drake, Steven K., Wehr, Nancy B., Weissman, Allan M., LaVaute, Timothy, Minato, Nagahiro, Klausner, Richard D., Levine, Rodney L., Rouault, Tracey A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1998
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560204/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.4924
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Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins

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