Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline

Silencing of genomic repeats, including transposable elements, in Drosophila melanogaster is mediated by repeat-associated short interfering RNAs (rasiRNAs) interacting with proteins of the Piwi subfamily. rasiRNA-based silencing is thought to be mechanistically distinct from both the RNA interferen...

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Autors principals: Klenov, Mikhail S., Lavrov, Sergey A., Stolyarenko, Anastasia D., Ryazansky, Sergey S., Aravin, Alexei A., Tuschl, Thomas, Gvozdev, Vladimir A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018648/
https://ncbi.nlm.nih.gov/pubmed/17702759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm576
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