Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Ψ55-synthase and RNA-guided RNA:Ψ-synthase activities

Protein aNOP10 has an essential scaffolding function in H/ACA sRNPs and its interaction with the pseudouridine(Ψ)-synthase aCBF5 is required for the RNA-guided RNA:Ψ-synthase activity. Recently, aCBF5 was shown to catalyze the isomerization of U55 in tRNAs without the help of a guide sRNA. Here we s...

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Detalhes bibliográficos
Main Authors: Muller, Sébastien, Fourmann, Jean-Baptiste, Loegler, Christine, Charpentier, Bruno, Branlant, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018633/
https://ncbi.nlm.nih.gov/pubmed/17704128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm606
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