Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein

Archaeal RNA:pseudouridine-synthase (PUS) Cbf5 in complex with proteins L7Ae, Nop10 and Gar1, and guide box H/ACA sRNAs forms ribonucleoprotein (RNP) catalysts that insure the conversion of uridines into pseudouridines (Ψs) in ribosomal RNAs (rRNAs). Nonetheless, in the absence of guide RNA, Cbf5 ca...

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Publicado no:Sci Rep
Main Authors: Fujikane, Ryosuke, Behm-Ansmant, Isabelle, Tillault, Anne-Sophie, Loegler, Christine, Igel-Bourguignon, Valérie, Marguet, Evelyne, Forterre, Patrick, Branlant, Christiane, Motorin, Yuri, Charpentier, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138745/
https://ncbi.nlm.nih.gov/pubmed/30218085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32164-0
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