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Desensitization of the neutrophil aggregation response to chemotactic factors.

In the presence of Ca2+ and Mg2+, the chemotactic fragment of C5, the synthetic chemotactic oligopeptide formyl-methionyl-leucyl-phenyl-alanine, and the ionophore A23187 aggregated human neutrophils. Aggregation induced by the two chemotactic factors was transient and reversed within 2 to 4 minutes...

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Autors principals: O'Flaherty, J. T., Kreutzer, D. L., Showell, H. S., Becker, E. L., Ward, P. A.
Format: Artigo
Idioma:Inglês
Publicat: 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018345/
https://ncbi.nlm.nih.gov/pubmed/717543
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