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Gentamicin and tobramycin nephrotoxicity. A morphologic and functional comparison in the rat.

Fischer 344 rats were treated with tobramycin or gentamicin, 40 mg/kg/day, for up to 10 days or with tobramycin, 120 mg/kg/day, for up to 14 days. Serum creatinine and BUN at the time of sacrifice were determined, and kidney tissues were examined by light and electron microscopy. Rats receiving gent...

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Autors principals: Houghton, D. C., Plamp, C. E., DeFehr, J. M., Bennett, W. M., Porter, G., Gilbert, D.
Format: Artigo
Idioma:Inglês
Publicat: 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018331/
https://ncbi.nlm.nih.gov/pubmed/696801
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