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Regulation of a nuclear export signal by an adjacent inhibitory sequence: The effector domain of the influenza virus NS1 protein

In the cell nucleus the NS1 protein of influenza A virus inhibits both pre-mRNA splicing and the nuclear export of mRNAs. Both the RNA-binding and effector domains of the protein are required for these nuclear functions. Here we demonstrate that the NS1 protein has a latent nuclear export signal (NE...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Li, Yongzhong, Yamakita, Yoshihiko, Krug, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.4864
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