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Regulation of a nuclear export signal by an adjacent inhibitory sequence: The effector domain of the influenza virus NS1 protein

In the cell nucleus the NS1 protein of influenza A virus inhibits both pre-mRNA splicing and the nuclear export of mRNAs. Both the RNA-binding and effector domains of the protein are required for these nuclear functions. Here we demonstrate that the NS1 protein has a latent nuclear export signal (NE...

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Autores principales: Li, Yongzhong, Yamakita, Yoshihiko, Krug, Robert M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC20179/
https://ncbi.nlm.nih.gov/pubmed/9560194
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