Hypertrophy and Heart Failure in Mice Overexpressing the Cardiac Sodium-Calcium Exchanger

BACKGROUND: The cardiac sodium–calcium exchanger (NCX1) is a key sarcolemmal protein for the maintenance of calcium homeostasis in the heart. Since heart failure is associated with increased expression of NCX1, heterozygous (HET) and homozygous (HOM) transgenic mice overexpressing NCX1 were develope...

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Autori principali: Roos, Kenneth P., Jordan, Maria C., Fishbein, Michael C., Ritter, Matthew R., Friedlander, Martin, Chang, Helen C., Rahgozar, Paymon, Han, Tieyan, Garcia, Alejandro J., MacLellan, W. Robb, Ross, Robert S., Philipson, Kenneth D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2017112/
https://ncbi.nlm.nih.gov/pubmed/17517353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2007.01.004
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