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Myocardial Function with Reduced Expression of the Sodium-Calcium Exchanger

BACKGROUND: The complete removal of the cardiac sodium-calcium exchanger (NCX1) is associated with embryonic lethality while its overexpression is linked to heart failure. To determine whether or not a reduced expression of NCX1 is compatible with normal heart structure and function, we studied two...

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Autores principales: Jordan, Maria C., Henderson, Scott. A., Han, Tieyan, Fishbein, Michael C., Philipson, Kenneth D., Roos, Kenneth P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929393/
https://ncbi.nlm.nih.gov/pubmed/20797603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2010.03.012
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