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Regulation of sodium channel gene expression by class I antiarrhythmic drugs and n − 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes

Previous studies have shown that chronic administration of class I antiarrhythmic drugs, which have definite inhibitory action on the fast Na(+) channel, result in up-regulation of cardiac Na(+) channel expression, and suggest that this effect may contribute to their deleterious effects during chron...

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Detalhes bibliográficos
Main Authors: Kang, Jing X., Li, Yunyuan, Leaf, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20157/
https://ncbi.nlm.nih.gov/pubmed/9122264
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