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A surface on the G protein β-subunit involved in interactions with adenylyl cyclases

Receptor activation of heterotrimeric G proteins dissociates Gα from the Gβγ complex, allowing both to regulate effectors. Little is known about the effector-interaction regions of Gβγ. We had used molecular modeling to dock a peptide encoding the region of residues 956–982 of adenylyl cyclase (AC)...

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Autors principals: Chen, Yibang, Weng, Gezhi, Li, Jinrong, Harry, Anya, Pieroni, Joseph, Dingus, Jane, Hildebrandt, John D., Guarnieri, Frank, Weinstein, Harel, Iyengar, Ravi
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20154/
https://ncbi.nlm.nih.gov/pubmed/9122261
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