Involvement of human liver cytochrome P4502B6 in the metabolism of propofol

AIMS: To determine the cytochrome P450 (CYP) isoforms involved in the oxidation of propofol by human liver microsomes. METHODS: The rate constant calculated from the disappearance of propofol in an incubation mixture with human liver microsomes and recombinant human CYP isoforms was used as a measur...

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Detalhes bibliográficos
Main Authors: Oda, Yutaka, Hamaoka, Naoya, Hiroi, Toyoko, Imaoka, Susumu, Hase, Ichiro, Tanaka, Kazuo, Funae, Yoshihiko, Ishizaki, Takashi, Asada, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2015030/
https://ncbi.nlm.nih.gov/pubmed/11298076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.00344.x
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