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CYP2D6 and CYP2C19 genotypes of patients with terodiline cardiotoxicity identified through the yellow card system
AIMS: Terodiline has concentration dependent QT prolonging effects and thus the potential for cardiotoxicity. Pharmacogenetic variation in terodiline metabolism could be responsible for cardiotoxicity. We sought to determine whether CYP2D6 (debrisoquine hydroxylase) or CYP2C19 (S-mephenytoin hydroxy...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014965/ https://ncbi.nlm.nih.gov/pubmed/10886124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00230.x |
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