Pharmacokinetics and pharmacodynamics of R- and S-gallopamil during multiple dosing

AIMS: Using a stable isotope technique we investigated the pharmacokinetics and pharmacodynamics of gallopamil after administration of 50 mg pseudoracemic gallopamil every 12 h for 7 doses (72 h). METHODS: Six male healthy volunteers were studied. After the seventh dose the pharmacokinetics and phar...

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Bibliographic Details
Main Authors: Gross, Annette S, Eichelbaum, Michel, Mörike, Klaus, Mikus, Gerd
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2000
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014898/
https://ncbi.nlm.nih.gov/pubmed/10671907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00115.x
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