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Modulation of the function of presynaptic α7 and non-α7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brain

BACKGROUND AND PURPOSE: Two metabolites of tryptophan, 5-hydroxyindole and kynurenic acid (kynurenate) affect the function of α7 nicotinic acetylcholine receptors (nAChRs), as measured by electrophysiological and Ca(2+) fluorescence techniques. To better understand the modulations by 5-hydroxyindole...

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Hlavní autoři: Grilli, M, Raiteri, L, Patti, L, Parodi, M, Robino, F, Raiteri, M, Marchi, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014664/
https://ncbi.nlm.nih.gov/pubmed/17016503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706914
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