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Antidystonic effects of K(v)7 (KCNQ) channel openers in the dt(sz) mutant, an animal model of primary paroxysmal dystonia
BACKGROUND AND PURPOSE: Mutations in neuronal K(v)7 (KCNQ) potassium channels can cause episodic neurological disorders. Paroxysmal dyskinesias with dystonia are a group of movement disorders which are regarded as ion channelopathies, but the role of K(v)7 channels in the pathogenesis and as targets...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014660/ https://ncbi.nlm.nih.gov/pubmed/17016514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706878 |
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